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The Secret Behind Silkworm's Hardy Stomachs


ScienceDaily (May 30, 2008) — Silkworms have a unique ability to eat toxic mulberry leaves without feeling ill, and researchers have come one step closer to understanding why: silkworms contain a special digestive enzyme that is not affected by mulberry's toxic chemicals. 

http://www.sciencedaily.com/releases/2008/05/080527170509.htm

Mulberry leaves contain an extremely high amount of alkaloids that inhibit enzymes that break down sucrose (sugar), and thus are potentially quite toxic. However, one type of sucrase called beta-fructofuranosidase is not affected by these alkaloids.

Until now, this enzyme has not been found in any animals, but Toru Shimada and colleagues believed this might explain the silkworm's unique diet.

The researchers scanned the silkworm genome and discovered two fructofuranosidase genes, although only one was actually expressed in the worm. This gene (BmSuc1) was, as expected, concentrated in the worm's gut, although surprisingly was also prevalent in the silk gland. When they isolated the enzyme from silkworms, the researchers found it could effectively digest sucrose.

Shimada and colleagues note that further work is needed to determine if this special enzyme is the sole reason for silkworm's resistance to mulberry toxins. It's possible that fructofuranosidases may turn up in other insects that cannot eat mulberry leaves, indicating additional factors are at work.

Journal reference:

  • Daimon et al. B-fructofuranosidase genes of the silkworm, Bombyx mori: insights into enzymatic adaptation of B. mori to toxic alkaloids in mulberry latex. Journal of Biological Chemistry, 2008; 283 (22): 15271 DOI: 10.1074/jbc.M709350200


  • Enhancing The Healthful Properties Of Silkwormshttp://www.sciencedaily.com/releases/2006/09/060904100914.htm

    ScienceDaily (Sep. 5, 2006) — The search for a food that can be enriched with healthful conjugated linoleic acid (CLA) has taken an unlikely twist -- straight toward the silkworm. An international group of scientists is reporting success in producing high-CLA silkworms.

    Although silkworm soufflé may not sound like the most appetizing dish, people in Asian countries treasure powdered silkworm as a nutritional supplement and traditional treatment for diabetes.

    CLA is an umbrella term for isomers -- chemical forms -- of linoleic acid, an essential fatty acid. Studies suggest that CLA may have a range of health benefits. They include stimulation of the immune system, protection against cancer and heart disease, reducing body fat and controlling diabetes. Those studies sparked efforts to produce high-CLA poultry, eggs and pigs by feeding CLA to animals. However, it has been difficult to get those animals to incorporate large amounts of CLAs.

    Yeong L. Ha and colleagues now report that silkworms fed CLA-coated mulberry leaves at a certain stage in their growth cycle accumulate large amounts of CLA. They began the research, scheduled for the July 12 issue of ACS' Journal of Agricultural and Food Chemistry, after other scientists found that houseflies accumulate CLA.

    "It is of great significance to produce silkworms containing CLA incorporated into the lipids of their bodies," Ha reported, adding that CLA may enhance the healthful properties of silkworm powder.

    Reference: "Production of Silkworms with Conjugated Linoleic Acid (CLA) Incorporated Into their Lipids by Dietary CLA." Journal of Agricultural and Food Chemistry

    --


    Ad http://www.asthmaaustralia.org.au/natmag/AsthmaUpdate-Jun08.pdf
    Naturally hypoallergenic - Ideal for allergy sufferers - silk is resistant to dust mite.

    [ pubmed house dust mite silk] finds
    scientific claims must be supported by robust and independently verifiable evidence.
    can't find hard science to back this claim.

    see:
    http://pediatrics.aappublications.org/cgi/content/abstract/107/5/e80
    http://ajrccm.atsjournals.org/cgi/content/abstract/163/5/1108

    ARTICLE
    http://www.beautysecretsblog.net/2008/02/16/are-silk-pillowcases-good-for-your-skin/ 

    showed me this link

    Clinical effectiveness of a silk fabric in the treatment of atopic dermatitis.
    <http://www.ncbi.nlm.nih.gov/pubmed/14746626?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstractPlusDrugs1>
    Clinical effectiveness of a silk fabric in the treatment of atopic dermatitis.
    Ricci G, Patrizi A, Bendandi B, Menna G, Varotti E, Masi M.

    Department of Paediatrics, University of Bologna, Via Massarenti 11, 40138 Bologna, Italy. ricci@med.unibo.it

    BACKGROUND: In children with atopic dermatitis (AD), eczema is easily aggravated by contact with irritant factors (e.g. aggressive detergents, synthetic and woollen clothes, climatic factors). OBJECTIVES: To evaluate the effectiveness of a special silk fabric (MICROAIR DermaSilk) in the treatment of young children affected by AD with acute lesions at the time of examination. METHODS: Forty-six children (mean age 2 years) affected by AD in an acute phase were recruited: 31 received special silk clothes (group A) which they were instructed to wear for a week; the other 15 served as a control group (group B) and wore cotton clothing. Topical moisturizing creams or emulsions were the only topical treatment prescribed in both groups. The overall severity of the disease was evaluated using the SCORAD index. In addition, the local score of an area covered by the silk clothes was compared with the local score of an uncovered area in the same child. All patients were evaluated at baseline and 7 days after the initial examination. RESULTS: At the end of the study a significant decrease in AD severity was observed in the children of group A (mean SCORAD decrease from 43 to 30; P = 0.003). At the same time, the improvement in the mean local score of the covered area (from 32 to 18.6; P = 0.001) was significantly greater than that of the uncovered area (from 31 to 26; P = 0.112). CONCLUSIONS: The use of special silk clothes may be useful in the management of AD in children.

    http://www.parliament.the-stationery-office.co.uk/pa/ld200607/ldselect/ldsctech/166/7041807.htm

    dustmites can't live in silk - debunked
    ASSESSMENT

    1.   Upheld

      The ASA considered that evidence from a study on specially treated silk clothing could not be extrapolated to a duvet that was filled with a different type of silk and had a cotton casing. We considered that the claim was misleading.

    2.   Upheld

      We noted that no evidence was presented to show that house dust mites were unable to live in silk-filled duvets or that a cotton-cased duvet would produce the improvements described in the study. We considered that the claims were misleading.

    3.   Upheld

      Because no evidence was presented to show that house dust mites were unable to live in silk filled duvets and because the duvet had a cotton casing, we considered that the claim was misleading.

    4.   Upheld

      We noted no evidence was presented to support the claim that the duvet would adjust to the body's temperature or be warm in the winter and cool in the summer. We considered that the claims were misleading.

    5.   Upheld

      We welcomed the broadcasters action but nevertheless considered that the claims were misleading.

      We concluded that the ads breached rules 5.1 (Misleading advertising) and 5.2.1 (Evidence) of the CAP (Broadcast) TV Advertising Standards Code.

    ACTION

      The ads must not be shown again in their present form and the products should not be advertised without adequate substantiation for the claims made.

    American Institute of Conservators
    http://www.quiltersmuse.com/straight_talk_chpt_4B.htm
    Dust mites were first seen by Anton van Leeuwenhoek in 1694 after he had invented the microscope. There are two types of mites: the North American House Dust Mite

    For those with known allergies to dust mites, it is recommended that you wash all bed sheets and (synthetic) blankets in hot water (130 degrees Fahrenheit), every other week. Avoid having wool blankets on the bed. Put washable covers on both pillows and mattresses. Home Trends sells a waterproof mattress pad that provides a special barrier for dust mites, and they also sell a new laundry additive called “de-mite.” For more information call 1 (800) 810-2340, or visit: www.ShopHomeTrends.com

    Washing quilts frequently is not recommended for their sake, but it is possible to air them often. A white sheet that is brand new and has been washed and dried is ideal for draping over the quilt if the quilt is laid over a clothesline outside. Large white, terry-cloth towels are just right for “padding” the clothesline, under the quilt. Of course, one would never hang a wet quilt at all. Unless your quilt is exceedingly old and decrepit, you should be able to hang it outside in the manner described.


    http://entomology.unl.edu/images/silkworm/silkworm.htm

    Silkworm Life Stages
    (Bombyx mori)

    All images, unless otherwise noted, were created by staff from the University of Nebraska
    Department of Entomology. They are freely available for use in publications and other media
    as long as the "Department of Entomology, University of Nebraska-Lincoln" and the
    photographer's name, if given, is credited. In no way should these images be copyrighted.

    Silkworm Moths Mating
    Female Silkworm Moth
    Depositing Eggs
    Young Silkworms Eating
    Mulberry Leaf
    Mature Silkworm Nearly
    Ready to Spin a Cocoon
    and Pupate
    Cluster of SilkwormCocoons
    Silkworm Cocoons with
    One Cut Open to View Pupa
    Silkworm Moth Emerging
    from Cocoon

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